Chelsea's 0-0 home draw with second-placed United ensured Thomas Tuchel is still undefeated in nine games since replacing Frank Lampard, but it meant they failed to dislodge fourth-placed West Ham United who became Manchester City's 20th successive victims in all competitions on Saturday.
Images from the English Premier League matches played on Saturday.
It promises to be a tense and thrilling finale to the season but Liverpool, who have frittered away a seven-point lead, will need to regain their momentum quickly if they are to push for their first league title since 1990.
Raheem Sterling struck twice as the Premier League champions Manchester City beat Crystal Palace 3-1 at Selhurst Park on Sunday to stay within two points of leaders Liverpool.
Images from Saturday's action in the Premier League.
Liverpool went into last Sunday's Merseyside derby on the back of five wins from their previous six league games but were held to a 1-1 draw at Anfield by Everton and then to a goalless stalemate at home against West Bromwich Albion on Wednesday.
Uruguay coach Oscar Tabarez was at a loss to explain how Luis Suarez missed three golden chances in his side's 1-0 win over Egypt in their opening World Cup Group A game but refused to blame his leading striker.
Chelsea reached the Champions League knock-out stage on Tuesday despite a 1-0 defeat by Basel in Group E after a late Mohamed Salah goal shocked the 2012 title winners, with Jose Mourinho saying they deserved to lose. Barcelona, without Lionel Messi but already into the last 16, went two goals down in Amsterdam but looked a different side in the second half after Ajax's Joel Veltman was sent off.
Atalanta's Josip Ilicic and Robin Gosens scored quickfire second-half goals to give them a comfortable 2-0 win over a toothless Liverpool
Roberto Firmino's 90th-minute header sent Liverpool back to the top of the Premier League with a 2-1 victory over Tottenham Hotspur, whose 11-match unbeaten run came to an end on Wednesday.
Liverpool stuttered into the quarter-finals of the Champions League with a 2-1 aggregate win over Inter Milan after suffering a 1-0 loss to the Italian side, who were reduced to 10 men, at Anfield on Tuesday.
Inter, Liverpool sweating on last-16 spots
City are two points behind leaders Liverpool, but have a game in hand
Roberto Firmino scored twice as Liverpool boosted their hopes of Champions League football next season
Images from the UEFA Champions League matches played on Wednesday night.
Roberto Firmino struck a stoppage-time winner as Liverpool beat Paris St Germain 3-2 at Anfield on Tuesday after Kylian Mbappe looked to have secured a point for the French side in a compelling Champions League Group C clash.
Liverpool overcame another obstacle on the path to what looks an almost certain Premier League title triumph as they chalked up a record-breaking 20th win
Liverpool are on course to shatter the English Premier League's record points haul and the way Juergen Klopp's side are churning out wins it would now be a surprise if they failed to do so. With 19 wins and a draw they are averaging 2.90 points per game, putting them on course for 110 from 38 games which would also be a record for Europe's top five leagues.
Images from Tuesday's action in the Premier League
Images from the English Premier League matches played on Sunday
A round-up of Sunday's action in the Premier League.
Megan Rapinoe earlier won the women's Ballon d'Or after leading the United States to a record-extending fourth World Cup title in France this year as they retained the trophy.
Arsenal beat Liverpool 5-4 on penalties on Saturday to lift the FA Community Shield, the curtain-raiser for the English domestic season, after the two sides played out a 1-1 draw on a chilly afternoon at Wembley.
Images from the Champions League matches played on Tuesday
Liverpool came into Saturday's Champions League final against Real Madrid on a wave of confidence but Zinedine Zidane's side showed exactly why they are the masters of Europe's top club competition in their 3-1 win.
Alexander-Arnold, seeing the Spanish club's defenders still getting organised, feigned to walk away from the corner before racing back to whip the ball to the unmarked Divock Origi, who clipped it past Marc-Andre ter Stegen.
Liverpool laboured to a 2-0 win over Denmark's Midtjylland on Tuesday as a goal from Diogo Jota and a Mohamed Salah penalty secured a hard-fought Champions League Group D victory at Anfield.
Edin Dzeko scored twice to set up a 3-1 win for AS Roma away to Napoli in the battle for second place in Serie A on Saturday and Paulo Dybala also notched up a brace for leaders Juventus in their 2-1 win over Udinese.
Inspirational manager Juergen Klopp has rekindled the Anfield flame though and delivered the club's 19th top-flight title, one behind arch-rivals United's record of 20, after finishing runners-up to City in a thrilling race last season.
Leaders Liverpool faltered in the English Premier League title race for the second time in six days as they were held to a 1-1 draw at West Ham United.
Liverpool won the Super Cup 5-4 on penalties against Chelsea
English Premier League leaders Liverpool opened up a 22-point gap at the top of the table with second-half goals from Alex Oxlade-Chamberlain, Jordan Henderson and a Mohamed Salah brace giving them a 4-0 home win over Southampton. A rare double from defender Antonio Rudiger earned Chelsea a point in an entertaining 2-2 draw with third-placed Leicester City.
Liverpool frustrated by 10-man Arsenal in League Cup semi stalemate
Leroy Sane struck the winner as Manchester City beat Liverpool 2-1 in a gripping English Premier League clash.
Match-by-match facts and statistics ahead of the Premier League fixtures on April 28-30
Champions Liverpool were ripped apart 7-2 at Aston Villa and Manchester United were humiliated 6-1 at home by Tottenham Hotspur on Sunday in one of the most astonishing days of Premier League results.
"I don't know how this affects my future," Valverde said.
Premier League champions Chelsea eased past a disappointing Everton with goals from Spaniards Cesc Fabregas and Alvaro Morata sealing a 2-0 victory on Sunday.
Liverpool made it three wins out of three as Mohamed Salah scored twice in a convincing 3-1 victory over Arsenal on Saturday to take control at the top of the Premier League.
AS Roma's Daniele De Rossi celebrated his 500th appearance for the club with a goal in their 3-1 win over Empoli at the Olympic Stadium as they moved up to second place in Serie A on Saturday.
